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1.
Global Spine J ; 13(7): 2007-2015, 2023 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-35216540

RESUMO

STUDY DESIGN: Questionnaire-based survey. OBJECTIVES: Surgical site infection (SSI) is a common complication in spine surgery but universal guidelines for SSI prevention are lacking. The objectives of this study are to depict a global status quo on implemented prevention strategies in spine surgery, common themes of practice and determine key areas for future research. METHODS: An 80-item survey was distributed among spine surgeons worldwide via email. The questionnaire was designed and approved by an International Consensus Group on spine SSI. Consensus was defined as more than 60% of participants agreeing to a specific prevention strategy. RESULTS: Four hundred seventy-two surgeons participated in the survey. Screening for Staphylococcus aureus (SA) is not common, whereas preoperative decolonization is performed in almost half of all hospitals. Body mass index (BMI) was not important for surgery planning. In contrast, elevated HbA1c level and hypoalbuminemia were often considered as reasons to postpone surgery. Cefazoline is the common drug for antimicrobial prophylaxis. Alcohol-based chlorhexidine is mainly used for skin disinfection. Double-gloving, wound irrigation, and tissue-conserving surgical techniques are routine in the operating room (OR). Local antibiotic administration is not common. Wound closure techniques and postoperative wound dressing routines vary greatly between the participating institutions. CONCLUSIONS: With this study we provide an international overview on the heterogeneity of SSI prevention strategies in spine surgery. We demonstrated a large heterogeneity for pre-, peri- and postoperative measures to prevent SSI. Our data illustrated the need for developing universal guidelines and for testing areas of controversy in prospective clinical trials.

2.
Surg Neurol Int ; 13: 193, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-35673646

RESUMO

Background: We analyzed the role of hypoalbuminemia, dialysis, and other risk factors that increase morbidity/ mortality following surgery for primary pyogenic spinal infections (PSIs). The American College of Surgeons' National Surgical Quality Improvement Program (ACS-NSQIP) that included 627 patients was utilized as our database. Methods: Primary spinal surgery for spondylodiscitis was evaluated in a ACS-NSQIP database involving 627 patients between 2010 and 2019. Outcome assessment included evaluation of 30-day postoperative morbidity, and mortality rates. Results: Within 30 postoperative days, complications occurred in 14.6% (92/627) of patients; 59 (9.4%) required readmission, and 39 (6.2%) required additional surgery. The most common complications were: wound infections, pneumonia, septic shock, and death (1.8%). Hypoalbuminemia (i.e., significantly associated with unplanned readmission and reoperation), and dialysis were the two major risk factors contributing to increased perioperative morbidity and mortality. Conclusion: Among 627 ACS-NSQIP patients undergoing primary surgery for PSIs, hypoalbuminemia and dialysis were associated with higher risks of major perioperative morbidity (i.e., within 30 postoperative days - mostly readmissions and reoperations) and mortality.

3.
Surg Neurol Int ; 11: 130, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-32547817

RESUMO

BACKGROUND: Intraoperative neurophysiological monitoring (IOM) has become valuable in spine surgery. Unfortunately, it is not always available in many spine centers, especially in developing countries. Our aim was to evaluate the accessibility and barriers to IOM in spine surgery in Latin America. METHODS: We designed a questionnaire to evaluate the characteristics of surgeons and their opinions on the usefulness of IOM for different spine operations. The survey was sent to 9616 members and registered users of AO Spine Latin America (AOSLA) from August 1, 2019, to August 21, 2019. Major variables studied included nationality, years of experience, specialty (orthopedics or neurosurgery), level of complexity of the hospital, number of spine surgeries performed per year by the spine surgeon, the types of spinal pathologies commonly managed, and how important IOM was to the individual surgeon. General questions to evaluate use included accessibility, limitations of IOM usage, management of IOM changes, and the legal value of IOM. The results were analyzed and compared between neurosurgeon and orthopedics, level of surgeon experience, and country of origin. RESULTS: Questionnaires were answered by 200 members of AOSLA from 16 different countries. The most common responses were obtained from orthopedic surgeons (62%), those with more than 10 years of practice (54%); majority of surgeons performed more than 50 spine surgeries per year (69%) and treated mainly spine degenerative diseases (76%). Most surgeons think that IOM has a real importance during surgeries (92%) and not just a legal value. Although surgeons mostly considered IOM essential to scoliosis surgery in adolescents (70%), thoracolumbar kyphosis correction (68%), and intramedullary tumors (68%), access to IOM was limited to 57% for economic reasons. Of interest, in 64% of cases, where IOM was available and significant change occurred, the actual operative procedures were significantly altered. CONCLUSION: Despite the fact that 68% of spine surgeons believe IOM to be indispensable for complex spine surgery, cost remains the main barrier to its use/availability in Latin America.

4.
Oper Neurosurg (Hagerstown) ; 18(3): E81, 2020 03 01.
Artigo em Inglês | MEDLINE | ID: mdl-31173144

RESUMO

We present the case of a meningioma of the foramen magnum, in a patient of age 62 yr, who presented at the time of surgery a hemiparesis on the right side at 2 mo of evolution. The patient gave his informed consent for the publication of the case, and approval was obtained from the research department of the hospital where the procedure was performed. The magnetic resonance imaging (MRI) in the mid-sagittal view shows a meningioma of the foramen magnum, with an extension in the posterior fossa and in the upper part of the cervical canal. In the coronal view and in the axial view, we can identify that although it is a meningioma of the anterior part of the foramen magnum, it is observed that the lesion has a displacement towards the right side. In a cadaveric specimen, we show the normal anatomy and the key landmarks for performing the approach. The patient was treated by a far lateral approach with a partial removal of the condyle. We show the craniectomy and the microsurgical technique for the tumor resection step by step. We paid particular attention in the anatomy surrounding the tumor and the tips and tricks for a safe resection. We reached a total resection with a good outcome; the result of the anatomopathological study confirmed the diagnosis of meningothelial meningioma. The dura was closed in a hermetic manner with a synthetic dura patch; then sealant was placed. The bone defect was corrected by placing a mesh in titanium. Then the flap was closed as usual. The patient has a good evolution with 1 yr of follow-up and without lesion in the control MRI.


Assuntos
Neoplasias Meníngeas , Meningioma , Neoplasias da Base do Crânio , Dura-Máter , Forame Magno/diagnóstico por imagem , Forame Magno/cirurgia , Humanos , Neoplasias Meníngeas/diagnóstico por imagem , Neoplasias Meníngeas/cirurgia , Meningioma/diagnóstico por imagem , Meningioma/cirurgia , Pessoa de Meia-Idade , Neoplasias da Base do Crânio/diagnóstico por imagem , Neoplasias da Base do Crânio/cirurgia
5.
Eur Spine J ; 27(Suppl 6): 925-945, 2018 09.
Artigo em Inglês | MEDLINE | ID: mdl-30151805

RESUMO

PURPOSE: Spine-related disorders are a leading cause of global disability and are a burden on society and to public health. Currently, there is no comprehensive, evidence-based model of care for spine-related disorders, which includes back and neck pain, deformity, spine injury, neurological conditions, spinal diseases, and pathology, that could be applied in global health care settings. The purposes of this paper are to propose: (1) principles to transform the delivery of spine care; (2) an evidence-based model that could be applied globally; and (3) implementation suggestions. METHODS: The Global Spine Care Initiative (GSCI) meetings and literature reviews were synthesized into a seed document and distributed to spine care experts. After three rounds of a modified Delphi process, all participants reached consensus on the final model of care and implementation steps. RESULTS: Sixty-six experts representing 24 countries participated. The GSCI model of care has eight core principles: person-centered, people-centered, biopsychosocial, proactive, evidence-based, integrative, collaborative, and self-sustaining. The model of care includes a classification system and care pathway, levels of care, and a focus on the patient's journey. The six steps for implementation are initiation and preparation; assessment of the current situation; planning and designing solutions; implementation; assessment and evaluation of program; and sustain program and scale up. CONCLUSION: The GSCI proposes an evidence-based, practical, sustainable, and scalable model of care representing eight core principles with a six-step implementation plan. The aim of this model is to help transform spine care globally, especially in low- and middle-income countries and underserved communities. These slides can be retrieved under Electronic Supplementary Material.


Assuntos
Atenção à Saúde/organização & administração , Doenças da Coluna Vertebral/terapia , Técnica Delfos , Carga Global da Doença , Humanos , Doenças da Coluna Vertebral/epidemiologia
6.
Eur Spine J ; 27(Suppl 6): 786-795, 2018 09.
Artigo em Inglês | MEDLINE | ID: mdl-30151808

RESUMO

PURPOSE: The purpose of this report is to describe the Global Spine Care Initiative (GSCI) contributors, disclosures, and methods for reporting transparency on the development of the recommendations. METHODS: World Spine Care convened the GSCI to develop an evidence-based, practical, and sustainable healthcare model for spinal care. The initiative aims to improve the management, prevention, and public health for spine-related disorders worldwide; thus, global representation was essential. A series of meetings established the initiative's mission and goals. Electronic surveys collected contributorship and demographic information, and experiences with spinal conditions to better understand perceptions and potential biases that were contributing to the model of care. RESULTS: Sixty-eight clinicians and scientists participated in the deliberations and are authors of one or more of the GSCI articles. Of these experts, 57 reported providing spine care in 34 countries, (i.e., low-, middle-, and high-income countries, as well as underserved communities in high-income countries.) The majority reported personally experiencing or having a close family member with one or more spinal concerns including: spine-related trauma or injury, spinal problems that required emergency or surgical intervention, spinal pain referred from non-spine sources, spinal deformity, spinal pathology or disease, neurological problems, and/or mild, moderate, or severe back or neck pain. There were no substantial reported conflicts of interest. CONCLUSION: The GSCI participants have broad professional experience and wide international distribution with no discipline dominating the deliberations. The GSCI believes this set of papers has the potential to inform and improve spine care globally. These slides can be retrieved under Electronic Supplementary Material.


Assuntos
Carga Global da Doença , Saúde Global , Doenças da Coluna Vertebral/epidemiologia , Técnica Delfos , Revelação , Medicina Baseada em Evidências , Humanos , Projetos de Pesquisa
7.
Eur Spine J ; 27(Suppl 6): 776-785, 2018 09.
Artigo em Inglês | MEDLINE | ID: mdl-30151809

RESUMO

PURPOSE: Spinal disorders, including back and neck pain, are major causes of disability, economic hardship, and morbidity, especially in underserved communities and low- and middle-income countries. Currently, there is no model of care to address this issue. This paper provides an overview of the papers from the Global Spine Care Initiative (GSCI), which was convened to develop an evidence-based, practical, and sustainable, spinal healthcare model for communities around the world with various levels of resources. METHODS: Leading spine clinicians and scientists around the world were invited to participate. The interprofessional, international team consisted of 68 members from 24 countries, representing most disciplines that study or care for patients with spinal symptoms, including family physicians, spine surgeons, rheumatologists, chiropractors, physical therapists, epidemiologists, research methodologists, and other stakeholders. RESULTS: Literature reviews on the burden of spinal disorders and six categories of evidence-based interventions for spinal disorders (assessment, public health, psychosocial, noninvasive, invasive, and the management of osteoporosis) were completed. In addition, participants developed a stratification system for surgical intervention, a classification system for spinal disorders, an evidence-based care pathway, and lists of resources and recommendations to implement the GSCI model of care. CONCLUSION: The GSCI proposes an evidence-based model that is consistent with recent calls for action to reduce the global burden of spinal disorders. The model requires testing to determine feasibility. If it proves to be implementable, this model holds great promise to reduce the tremendous global burden of spinal disorders. These slides can be retrieved under Electronic Supplementary Material.


Assuntos
Carga Global da Doença , Saúde Global , Doenças da Coluna Vertebral/epidemiologia , Dor nas Costas , Procedimentos Clínicos , Técnica Delfos , Países em Desenvolvimento , Medicina Baseada em Evidências , Humanos
8.
World Neurosurg ; 117: 301-308, 2018 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-29902610

RESUMO

BACKGROUND AND IMPORTANCE: Lesions located lateral to the lower brainstem, such as proximal posterior inferior cerebellar artery (PICA) aneurysms, are surgically challenging. We report a case of a patient with a left proximal PICA aneurysm that was successfully clipped via a so-called "extended" suboccipital subtonsillar approach, which allowed us to obtain proper vascular control without removal of the atlas. The anatomy relevant for this approach has been studied. METHODS: Three adult cadaveric heads were studied. The relevant neurovascular anatomy related to this approach was exposed. Hence, this technique was applied on the patient herewith reported. CASE PRESENTATION: A 60-year-old man with sudden onset of severe headache, nausea, and vomiting was admitted to our hospital. Computed tomography of the brain showed diffuse subarachnoid hemorrhage, mainly distributed at the level of the perimesencephalic cisterns. Cerebral angiography revealed a 3-mm aneurysm arising at the origin of the left PICA. The aneurysm was considered unsuitable for coil embolization, so it was treated via a "modified" posterolateral suboccipital subtonsillar route. The modification consisted of accomplishing proper proximal vascular control at the extracranial segment of the vertebral artery (V3), without the need of further removal of the posterior portion of the atlas. The patient was discharged neurologically intact. CONCLUSIONS: The technique we suggested allowed no unnecessary removal of bone, with no need to drill the occipital condyle or remove the atlas, offered proper proximal vascular control in the early stage of the surgical procedure, and limited the quantity of temporary vascular clips inside the intracranial surgical field.


Assuntos
Aneurisma Roto/cirurgia , Artérias/cirurgia , Cerebelo/irrigação sanguínea , Aneurisma Intracraniano/cirurgia , Procedimentos Neurocirúrgicos/métodos , Aneurisma Roto/diagnóstico por imagem , Aneurisma Roto/patologia , Artérias/anatomia & histologia , Artérias/diagnóstico por imagem , Artérias/patologia , Cerebelo/anatomia & histologia , Cerebelo/diagnóstico por imagem , Cerebelo/patologia , Humanos , Aneurisma Intracraniano/diagnóstico por imagem , Aneurisma Intracraniano/patologia , Masculino , Pessoa de Meia-Idade
9.
World Neurosurg ; 112: e823-e829, 2018 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-29410173

RESUMO

BACKGROUND: Spine surgeons are exposed to high amounts of radiation from fluoroscopic procedures during their lifetime. In this study, we evaluated spine surgeons' knowledge of and attitude regarding radiation exposure during spine surgery. METHODS: We developed a questionnaire including questions about surgeons' characteristics and knowledge of and attitude regarding radiation exposure during spine surgery. A survey was performed with the members of AOSpine Latin America. The main variables studied were specialty, years of experience, surgeon's position during fluoroscopy, and practices to reduce the patient's and surgeon's radiation exposure during surgery. The results were analyzed and compared among different specialties, levels of experience, and countries of origin. RESULTS: The questionnaire was answered by 371 members of AOSpine Latin America from different countries. The sample was mostly from orthopedic surgeons (57.1%) and surgeons in practice for longer than 10 years (54.2%). Thyroid lead protection was used by 64.2% of the spine surgeons, lead glasses by 20.2%, and lead gloves by 7%. A dosimeter badge was never or only rarely used by 75.7%. The correct answer for surgeon position during lateral lumbar fluoroscopy was reported by only one-third of the surgeons. The reported rate of thyroid protector use was higher in surgeons from Brazil and Colombia compared with surgeons from Mexico and Argentina (P < 0.001), whereas the use of pulsed-mode fluoroscopy was higher in Mexico and Argentina compared with Brazil and Colombia (P < 0.0001). CONCLUSIONS: Future efforts toward implementing educational programs in Latin America focused on safety strategies are needed to minimize intraoperative radiation exposure.


Assuntos
Conhecimentos, Atitudes e Prática em Saúde , Neurocirurgiões , Cirurgiões Ortopédicos , Exposição à Radiação , Estudos Transversais , Humanos , América Latina , Exposição Ocupacional/prevenção & controle , Exposição à Radiação/prevenção & controle , Lesões por Radiação/prevenção & controle , Inquéritos e Questionários
10.
J Clin Neurosci ; 21(12): 2219-25, 2014 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-25092274

RESUMO

Despite technological advances, such as intraoperative MRI, intraoperative sensory and motor monitoring, and awake brain surgery, brain anatomy and its relationship with cranial landmarks still remains the basis of neurosurgery. Our objective is to describe the utility of anatomical knowledge of brain sulci and gyri in neurosurgery. This study was performed on 10 human adult cadaveric heads fixed in formalin and injected with colored silicone rubber. Additionally, using procedures done by the authors between June 2006 and June 2011, we describe anatomical knowledge of brain sulci and gyri used to manage brain lesions. Knowledge of the brain sulci and gyri can be used (a) to localize the craniotomy procedure, (b) to recognize eloquent areas of the brain, and (c) to identify any given sulcus for access to deep areas of the brain. Despite technological advances, anatomical knowledge of brain sulci and gyri remains essential to perform brain surgery safely and effectively.


Assuntos
Encéfalo/anatomia & histologia , Encéfalo/cirurgia , Humanos , Procedimentos Neurocirúrgicos
11.
Surg Neurol Int ; 2: 164, 2011.
Artigo em Inglês | MEDLINE | ID: mdl-22140649

RESUMO

BACKGROUND: The central sulcus may be located through magnetic resonance imaging (MRI) by identifying the ipsilateral inverted Omega shape. In a brain with a lesion in this area, its identification becomes a hard task irrespective of the technique applied. The aim of this study is to show the usefulness of the contralateral Omega sign for the location of tumors in and around the central sulcus. We do not intend to replace modern techniques, but to show an easy, cheap and relatively effective way to recognize the relationship between the central sulcus and the lesion. METHODS: From July 2005 through December 2010, 43 patients with lesions in and around the central sulcus were operated using the contralateral Omega sign concept. Additionally, 5 formalin-fixed brains (10 hemispheres) were studied to clarify the anatomy of the central sulcus where the Omega shape is found. RESULTS: The central sulcus has three genua. The middle genu is characterized by an inverted Omega-shaped area in axial sections known as the Omega sign. On anatomical specimens, Omega was 11.2 ± 3.35 mm in height, on average, and 18.7 ± 2.49 mm in width, at the base. The average distance from the medial limit of the Omega to the medial edge of the hemisphere was 24.5 ± 5.35 mm. Identification of the Omega sign allowed for the topographic localization of the contralateral central sulcus in all our surgical cases but one. CONCLUSION: The contralateral Omega sign can be easily and reliably used to clarify the topographic location of the pathology. Hence, it gives a quick preoperative idea of the relationships between the lesion and the pre- and post-central gyri.

12.
Arq Neuropsiquiatr ; 69(2B): 365-70, 2011.
Artigo em Inglês | MEDLINE | ID: mdl-21625767

RESUMO

UNLABELLED: Epineural stitches are a means to avoid tension in a nerve suture. We evaluate this technique, relative to interposed grafts and simple neurorraphy, in a rat model. METHOD: Twenty rats were allocated to four groups. For Group 1, sectioning of the sciatic nerve was performed, a segment 4 mm long discarded, and epineural suture with distal anchoring stitches were placed resulting in slight tension neurorraphy. For Group 2, a simple neurorraphy was performed. For Group 3, a 4 mm long graft was employed and Group 4 served as control. Ninety days after, reoperation, latency of motor action potentials recording and axonal counts were performed. Inter-group comparison was done by means of ANOVA and the non-parametric Kruskal-Wallis test. RESULTS: The mean motor latency for the simple suture (2.27±0.77 ms) was lower than for the other two surgical groups, but lower than among controls (1.69±0.56 ms). Similar values were founding in both group 1 (2.66±0.71 ms) and group 3 (2.64±0.6 ms). When fibers diameters were compared a significant difference was identified between groups 2 and 3 (p=0.048). CONCLUSION: Good results can be obtained when suturing a nerve employ with epineural anchoring stitches. However, more studies are needed before extrapolating results to human nerve sutures.


Assuntos
Axônios , Regeneração Nervosa/fisiologia , Nervos Periféricos/cirurgia , Técnicas de Sutura , Animais , Axônios/patologia , Axônios/fisiologia , Eletrofisiologia , Masculino , Modelos Animais , Distribuição Aleatória , Ratos , Resistência à Tração
13.
J Clin Neurosci ; 17(10): 1298-300, 2010 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-20619658

RESUMO

We aimed to determine the position, number and variability of the sphenoid sinus ostia. A total of 32 dry skulls were examined under x6 magnification. The septum and nasal turbinates were removed to expose the anterior wall of the sphenoid sinus. A caliper was used for measurements. We found 2 ostia per skull, except for one (3%), in which the left ostium was absent. The inferior edges of both ostia were found at the same height in only four skulls (12.5%), and the superior edges of both ostia were found at the same height in only one skull (3%). Thus, in 27 skulls (84%) the lower and upper margins of both ostia were at different levels. The distance from the internal edge of the right ostium to the midline was 2.04mm on average (range: 0.3-5.3mm). The distance from the internal edge of the left ostium to the midline was 2.18mm on average (range: 0.2 to 5.1mm). In most skulls, the sphenoid ostia are located at different heights on each side; also a great variability in the distance from the internal border of the ostia to the midline was found. We found this anatomical knowledge useful when performing a transsphenoidal approach to the sella turcica.


Assuntos
Microcirurgia/métodos , Osso Esfenoide/anatomia & histologia , Osso Esfenoide/cirurgia , Seio Esfenoidal/anatomia & histologia , Seio Esfenoidal/cirurgia , Humanos
14.
J Pediatr Hematol Oncol ; 32(5): e202-6, 2010 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-20523247

RESUMO

BACKGROUND: Glioblastomas occur infrequently in children, and the prognosis is better than for glioblastomas seen in adults. Aggressive treatment is justified in pediatric patients. OBSERVATIONS: We present the case of a 6-year-old child with malignant posterior temporal glioma treated with surgery, radiotherapy, local chemotherapy with carmustine wafers, and oral therapy with temozolomide, both at initial diagnosis and at relapse 18 months later. After 6 years, the patient seems healthy with no focal neurologic signs, and imaging studies show no evidence of disease. CONCLUSION: Multimodal therapy was found to have a very positive outcome for a child with malignant glioma.


Assuntos
Protocolos de Quimioterapia Combinada Antineoplásica/uso terapêutico , Neoplasias Encefálicas/tratamento farmacológico , Glioblastoma/tratamento farmacológico , Neoplasias Encefálicas/patologia , Carmustina/administração & dosagem , Criança , Terapia Combinada , Craniotomia , Dacarbazina/administração & dosagem , Dacarbazina/análogos & derivados , Glioblastoma/patologia , Humanos , Imageamento por Ressonância Magnética , Retratamento , Temozolomida , Resultado do Tratamento
15.
Rev. argent. neurocir ; 23(2): 71-76, abr.-jun. 2009. ilus
Artigo em Espanhol | LILACS | ID: lil-560006

RESUMO

Objetivo. Documentar la utilidad de una técnica de sutura epineural bajo tensión, en comparación con la sutura mediante injerto interpuesto y la neurorrafia termino-terminal, en un estudio realizado en un modelo experimental animal (rata Wistar). Material y Método. Un lote de 20 animales, considerados como 40 unidades fisiológicas independientes a nivel del miembro inferior, fueron separados en 4 grupos de 10: en el primero se realizó una sutura bajo tensión con puntos epineurales a nivel del nervio ciático luego de resecar 4 mm de nervio. En el segundo se realizó una sutura término-terminal sin tensión, en el tercero se colocó un puente de injerto autólogo de 4 mm de extensión y el cuarto fue utilizado como control. A los 90 días de efectuados los procedimientos, se reexpusieron las zonas operadas y se documentaron las respuestas fisiológicas a los diferentes tipos de sutura mediante potenciales de acción de músculo (PAM) y nervio (PAN). Resultados. El promedio de la velocidad de conducción para la sutura simple fue el mejor de los tres grupos operados (14,60 mm/ ms), aunque peor que el control (19,31 mm/ms). La sutura a tensión mediante puntos epineurales (12,02 mm/ms) demostró resultados neurofisiológicos superiores que cuando se utilizó injerto autólogo (11,09 mm/ms). Conclusión. El presente estudio demuestra que si se logra coaptar un nervio ciático de rata mediante sutura epineural con puntos distales a la línea de neurorrafia, sus resultados son mejores que al emplear injerto. Sin embargo, estos resultados, obtenidos en un modelo de animal pequeño, deben ser cuidadosamente extrapolados a la práctica quirúrgica habitual.


Objective. To measure the utility of this technique, in comparison with interposed grafts and termino-terminal neuroraphy, all applied in an experimental model (Wistar rat).Materials and method. 20 rats were used in both sides (40 legs, each one considered as independent physiological units, were grouped in four groups: in the first one, a section of thesciatic nerve was performed, a segment 4mm long was discarded and an epineural suture with distal anchoring stitches was done under slight tension. In the second group a tensionlesstermino-terminal neuroraphy was performed after sciatic nerve section. In the third group a 4 mm long graft was employed and the fourth was used as control. 90 days after this procedure, the animals were reoperated and muscle and nerve action potentialswere recorded in both sides. Results. The mean conduction velocity for the simple suture was higher than the other two groups, but lower than the control(19,31 mm/ms). Neuroraphy with epineural stitches (12,02 mm/ms) was better than when an autologous nerve graft was employed (11,09 mm/ms).Conclusion. This study demonstrates that a good result can be obtained if a nerve is sutured under slight tension, employing epineural anchoring stitches. Nevertheless, more studies shouldbe performed before applying these results to human nerve suture.


Assuntos
Ratos Wistar , Técnicas de Sutura
16.
Rev. argent. neurocir ; 23(2): 71-76, abr.-jun. 2009. ilus
Artigo em Espanhol | BINACIS | ID: bin-124390

RESUMO

Objetivo. Documentar la utilidad de una técnica de sutura epineural bajo tensión, en comparación con la sutura mediante injerto interpuesto y la neurorrafia termino-terminal, en un estudio realizado en un modelo experimental animal (rata Wistar). Material y Método. Un lote de 20 animales, considerados como 40 unidades fisiológicas independientes a nivel del miembro inferior, fueron separados en 4 grupos de 10: en el primero se realizó una sutura bajo tensión con puntos epineurales a nivel del nervio ciático luego de resecar 4 mm de nervio. En el segundo se realizó una sutura término-terminal sin tensión, en el tercero se colocó un puente de injerto autólogo de 4 mm de extensión y el cuarto fue utilizado como control. A los 90 días de efectuados los procedimientos, se reexpusieron las zonas operadas y se documentaron las respuestas fisiológicas a los diferentes tipos de sutura mediante potenciales de acción de músculo (PAM) y nervio (PAN). Resultados. El promedio de la velocidad de conducción para la sutura simple fue el mejor de los tres grupos operados (14,60 mm/ ms), aunque peor que el control (19,31 mm/ms). La sutura a tensión mediante puntos epineurales (12,02 mm/ms) demostró resultados neurofisiológicos superiores que cuando se utilizó injerto autólogo (11,09 mm/ms). Conclusión. El presente estudio demuestra que si se logra coaptar un nervio ciático de rata mediante sutura epineural con puntos distales a la línea de neurorrafia, sus resultados son mejores que al emplear injerto. Sin embargo, estos resultados, obtenidos en un modelo de animal pequeño, deben ser cuidadosamente extrapolados a la práctica quirúrgica habitual.(AU)


Objective. To measure the utility of this technique, in comparison with interposed grafts and termino-terminal neuroraphy, all applied in an experimental model (Wistar rat).Materials and method. 20 rats were used in both sides (40 legs, each one considered as independent physiological units, were grouped in four groups: in the first one, a section of thesciatic nerve was performed, a segment 4mm long was discarded and an epineural suture with distal anchoring stitches was done under slight tension. In the second group a tensionlesstermino-terminal neuroraphy was performed after sciatic nerve section. In the third group a 4 mm long graft was employed and the fourth was used as control. 90 days after this procedure, the animals were reoperated and muscle and nerve action potentialswere recorded in both sides. Results. The mean conduction velocity for the simple suture was higher than the other two groups, but lower than the control(19,31 mm/ms). Neuroraphy with epineural stitches (12,02 mm/ms) was better than when an autologous nerve graft was employed (11,09 mm/ms).Conclusion. This study demonstrates that a good result can be obtained if a nerve is sutured under slight tension, employing epineural anchoring stitches. Nevertheless, more studies shouldbe performed before applying these results to human nerve suture.(AU)


Assuntos
Técnicas de Sutura , Ratos Wistar
17.
Rev. argent. neurocir ; 21(4): 163-172, oct.-dic. 2007. ilus, tab
Artigo em Espanhol | LILACS | ID: lil-511285

RESUMO

Objetivo: Determinar la utilidad de la identificación del surco central contralateral a la lesión, a través de Omega invertida, como método para localizar la corteza sensitivomotora adyacente al proceso tumoral. Método: Desde julio de 2005 hasta abril de 2007, fueron operadas por el primer autor (AC) 15 pacientes con lesiones cercanas o a nivel de la corteza sensitivomotora, utilizando el signo de Omega contralateral a la lesión. Además, fueron estudiados 5 cerebros (10 hemisferios) de cadáveres adultos fijados en formol. Resultados: El surco central separa la corteza motora de la sensitiva. Presenta tres rodillas o curvas. La rodilla media, es la resposable de la forma de Omega invertida que muestra el surco central en un corte axial. En promedio, la altura de Omega fue de 11.2mm +/- 3.35mm, y el ancho, en su base, de 15.7mm +/- 2.48mm. Por otro lado, la distancia promedio desde el borde medial de Omega hasta la línea media fue de 24.5mm +/- 5.35mm. En los 15 casos se estudió detenidamente la resonancia magnética (corte axial) antes de la cirugía, para poder identificar el surco central a través del signo de Omega, en el hemisferio contralateral a la lesión. En todos los casos excepto uno, fue posible identificar dicho signo. De los quince pacientes operados, siete mostraron déficit motor previo a la cirugía (1 plejía, 1 paresia severa, 1 paresia moderada y 4 paresias leves). En todos los casos hubo una mejoría en el postoperatorio. Los ocho pacientes restantes no presentaron déficit motor antes de la cirugía. Luego del procedimiento quirúrgico, dichos enfermos continuaron sin presentar déficit motor. Conclusión: El signo de Omega contralateral puede, fácil y eficientemente, ser utilizado para identificar la relación entre una lesión y el surco central ipsilateral.


Assuntos
Neoplasias Encefálicas , Craniotomia , Imageamento por Ressonância Magnética , Microcirurgia
18.
Rev. neurocir ; 8(2): 52-55, jun.-ago. 2006. ilus, graf
Artigo em Espanhol | LILACS | ID: lil-439590

RESUMO

La diastematomielia es una forma rara de disrafia espinal (menos del tres por ciento de los casos con disrafismo espinal oculto), más frecuente en el sexo femenino y en los niños. Clínicamente se manifiesta por tres grupos de sínfromes: alteraciones cutáneas, deformidades ortopédicas y síntomas o signos de disfunción neurológica, La asociación con otras malformaciónes raquimedulares está claramente documentada. Presentamos nuestra experiencia de los últimos treinta y seis meses con seis casos de diastomatomielia, de las cuales cuatro se presentaron asociadas a otra patología malformativa raquimedular. A pesar de ser una entidad poco frecuente debe tenerse presente a la hora de la resolución quirúrgica de las distintas malformaciones raquimedulares ya que tratada oportunamente la presencia de diastematomielia no empeora el pronóstico de la patología de base.


Assuntos
Humanos , Pré-Escolar , Adolescente , Recém-Nascido , Lactente , Criança , Anormalidades Congênitas , Defeitos do Tubo Neural , Disrafismo Espinal , Síndromes Neurocutâneas
19.
Rev. neurocir ; 8(2): 52-55, jun.-ago. 2006. ilus, graf
Artigo em Espanhol | BINACIS | ID: bin-122055

RESUMO

La diastematomielia es una forma rara de disrafia espinal (menos del tres por ciento de los casos con disrafismo espinal oculto), más frecuente en el sexo femenino y en los niños. Clínicamente se manifiesta por tres grupos de sínfromes: alteraciones cutáneas, deformidades ortopédicas y síntomas o signos de disfunción neurológica, La asociación con otras malformaciónes raquimedulares está claramente documentada. Presentamos nuestra experiencia de los últimos treinta y seis meses con seis casos de diastomatomielia, de las cuales cuatro se presentaron asociadas a otra patología malformativa raquimedular. A pesar de ser una entidad poco frecuente debe tenerse presente a la hora de la resolución quirúrgica de las distintas malformaciones raquimedulares ya que tratada oportunamente la presencia de diastematomielia no empeora el pronóstico de la patología de base. (AU)


Assuntos
Humanos , Pré-Escolar , Adolescente , Recém-Nascido , Lactente , Criança , Defeitos do Tubo Neural , Anormalidades Congênitas , Disrafismo Espinal , Síndromes Neurocutâneas
20.
Rev. neurocir ; 8(2): 52-55, jun.-ago. 2006. ilus, graf
Artigo em Espanhol | BINACIS | ID: bin-119647

RESUMO

La diastematomielia es una forma rara de disrafia espinal (menos del tres por ciento de los casos con disrafismo espinal oculto), más frecuente en el sexo femenino y en los niños. Clínicamente se manifiesta por tres grupos de sínfromes: alteraciones cutáneas, deformidades ortopédicas y síntomas o signos de disfunción neurológica, La asociación con otras malformaciónes raquimedulares está claramente documentada. Presentamos nuestra experiencia de los últimos treinta y seis meses con seis casos de diastomatomielia, de las cuales cuatro se presentaron asociadas a otra patología malformativa raquimedular. A pesar de ser una entidad poco frecuente debe tenerse presente a la hora de la resolución quirúrgica de las distintas malformaciones raquimedulares ya que tratada oportunamente la presencia de diastematomielia no empeora el pronóstico de la patología de base. (AU)


Assuntos
Humanos , Pré-Escolar , Adolescente , Recém-Nascido , Lactente , Criança , Defeitos do Tubo Neural , Anormalidades Congênitas , Disrafismo Espinal , Síndromes Neurocutâneas
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